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Posts Tagged ‘sham acupuncture’

There are several vedio online, posted by NCCIH, regarding to acupuncture research methodology.

    1. NCCIH

      • Active 1 month ago
      • 139 videos
      This is the official YouTube channel for the National Center for Complementary and Integrative Health (NCCIH) at the National …
      • CHANNEL

      1,408

    2. Acupuncture Studies

      • 7 months ago
      • 884 views
      In this clip (5 of 9), Dr. Deyo discusses some examples of studies on acupuncture. This clip is part of the lecture “Manipulating the …
      • HD
      • CC
    3. Comparative Effectiveness Research

      • 1 year ago
      • 675 views
      In this clip (8 of 9), how acupuncture can contribute to comparative effectivenessresearch is discussed. This clip is part of the lecture
      • HD
      • CC
    4. Data on Acupuncture’s Efficacy and Effectiveness

      • 1 year ago
      • 1,340 views
      In this clip (4 of 9), several recent studies on acupuncture’s efficacy and effectiveness are discussed. This clip is part of the lecture …
      • HD
      • CC
    5. Safety of Acupuncture

      • 1 year ago
      • 1,021 views
      In this clip (2 of 9): Results are presented from some large observational studies in the U.K. and Germany on the safety of …
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      • CC
    6. Acupuncture: Diverse Points of View

      • 1 year ago
      • 1,352 views
      In this clip (1 of 9): Acupuncture is a highly debated topic, as seen, for example, in the media. This clip is part of the lecture …
      • HD
      • CC
    7. Acupuncture Styles; Individual Treatment Response

      • 1 year ago
      • 676 views
      In this clip (6 of 9), the speaker addresses: (1) Do different acupuncture styles matter with respect to outcomes? (2) Are there …
      • HD
      • CC
    8. Neuroimaging and Stimulation Studies

      • 1 year ago
      • 834 views
      In this clip (5 of 9), the speaker addresses brain imaging with fMRI on acupunctureand then a controlled study on stimulated vs.
      • HD
      • CC
    9. Where Should We Go?

      • 1 year ago
      • 607 views
      In this clip (9 of 9), Dr. Witt discusses important areas for future acupuncture research. This clip is part of the lecture “International …
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      • CC
    10. Testing Hypotheses About Acupuncture

      • 1 year ago
      • 209 views
      In this clip (6 of 11), the speaker discusses some studies, including at the Martinos Center for Biomedical Imaging, on the …
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    11. Some Considerations in Clinical Studies

      • 1 year ago
      • 997 views
      In this clip (3 of 9), Dr. Witt discusses measuring benefit to patients, and matchingresearch questions with study types, in clinical …
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    12. Dr. Rick Deyo discusses research for chronic low back pain

      • 5 months ago
      • 37 views
      Dr. Deyo explains why he began studying complementary therapies for chronic low back pain. To learn more about the research …
      • HD
    13. Where Do We Stand?

      • 1 year ago
      • 603 views
      In this clip (7 of 9), the speaker offers five summary points from the acupuncture research and discusses a paper on clinical …
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    14. Historical Perspective on Chiropractic and Acupuncture

      • 7 months ago
      • 999 views
      In this clip (1 of 9): Dr. Deyo gives a brief history of chiropractic and acupuncture, especially as related to the mutual mistrust and …
      • HD
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    15. CAM Therapies: Neurostimulation and Acupuncture

      • 1 year ago
      • 1,026 views
      In this clip (7 of 10): Acupuncture and deep brain stimulation have strong placebo effects, and may do so through different brain …
      • CC
    16. Introduction to Neurobiological Correlates of Acupuncture

      • 1 year ago
      • 266 views
      In this clip (1 of 11): Acupuncture has been practiced for thousands of years in various parts of the world and has become popular …
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    17. How can we use functional imaging to look at the therapeutic effect of acupuncture?

      • 1 year ago
      • 128 views
      In this clip (8 of 11): Carpal tunnel syndrome is a condition for which acupuncture is used; this has been a research topic at the …
      • CC

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How large are the nonspecific effects of acupuncture? A meta-analysis of randomized controlled trials.

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http://www.biomedcentral.com/1741-7015/8/75

How large are the nonspecific effects of acupuncture? A meta-analysis of randomized controlled trials

Klaus Linde1*, Karin Niemann1, Antonius Schneider1 and Karin Meissner12

Author Affiliations

1Institute of General Practice, Technische Universität München, Orleansstrasse 47, D-81667 Munich, Germany

2Institute of Medical Psychology, Ludwig-Maximilians-University, Goethestrasse 31, D-80336 Munich, Germany

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BMC Medicine 2010, 8:75  doi:10.1186/1741-7015-8-75

The electronic version of this article is the complete one and can be found online at:http://www.biomedcentral.com/1741-7015/8/75

Abstract

Background

While several recent large randomized trials found clinically relevant effects of acupuncture over no treatment or routine care, blinded trials comparing acupuncture to sham interventions often reported only minor or no differences. This raises the question whether (sham) acupuncture is associated with particularly potent nonspecific effects. We aimed to investigate the size of nonspecific effects associated with acupuncture interventions.

Methods

MEDLINE, Embase, Cochrane Central Register of Controlled Clinical Trials and reference lists were searched up to April 2010 to identify randomized trials of acupuncture for any condition, including both sham and no acupuncture control groups. Data were extracted by one reviewer and verified by a second. Pooled standardized mean differences were calculated using a random effects model with the inverse variance method.

Results

Thirty-seven trials with a total of 5754 patients met the inclusion criteria. The included studies varied strongly regarding patients, interventions, outcome measures, methodological quality and effect sizes reported. Among the 32 trials reporting a continuous outcome measure, the random effects standardized mean difference between sham acupuncture and no acupuncture groups was -0.45 (95% confidence interval, -0.57, -0.34; I2 = 54%; Egger’s test for funnel plot asymmetry, P= 0.25). Trials with larger effects of sham over no acupuncture reported smaller effects of acupuncture over sham intervention than trials with smaller nonspecific effects (β = -0.39, P = 0.029).

Conclusions

Sham acupuncture interventions are often associated with moderately large nonspecific effects which could make it difficult to detect small additional specific effects. Compared to inert placebo interventions, effects associated with sham acupuncture might be larger, which would have considerable implications for the design and interpretation of clinical trials.

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