Research Information for Modified Huo Luo Xiao Ling Dan, Posted by Dr.Arthur Yin Fan

There are six papers in http://www.PubMed.gov, a NIH database for Modified Huo Luo Xiao Ling Dan, Dr.Arthur Yin Fan involved in most of these studies, included in pre-clinical studies for safety evaluation and efficacy tests, mechanism explorations. This project was a NIH funded studies conducted in University of Maryland Harvard University.

 1. Anti-hyperalgesic and anti-inflammatory effects of the modified Chinese herbal formula Huo Luo Xiao Ling Dan (HLXL) in rats.

Lao L, Fan AY, Zhang RX, Zhou A, Ma ZZ, Lee DY, Ren K, Berman B.

Am J Chin Med. 2006;34(5):833-44.

PMID:17080548 [PubMed – indexed for MEDLINE]Related citations

2.Extract of the Chinese herbal formula Huo Luo Xiao Ling Dan inhibited adjuvant arthritis in rats.

Zhang RX, Fan AY, Zhou AN, Moudgil KD, Ma ZZ, Lee DY, Fong HH, Berman BM, Lao L.

J Ethnopharmacol. 2009 Jan 30;121(3):366-71. Epub 2008 Nov 28.

PMID: 19100323 [PubMed – indexed for MEDLINE] Free PMC Article, Related citations

3.Huo-Luo-Xiao-Ling Dan modulates antigen-directed immune response in adjuvant-induced inflammation.

Rajaiah R, Lee DY, Ma Z, Fan AY, Lao L, Fong HH, Berman BM, Moudgil KD.

J Ethnopharmacol. 2009 May 4;123(1):40-4. Epub 2009 Mar 4.

PMID: 19429337 [PubMed – indexed for MEDLINE] Free PMC Article, Related citations

4.Preclinical safety evaluation of the aqueous acetone extract of Chinese herbal formula Modified Huo Luo Xiao Ling Dan.

Fan AY, Lao L, Zhang RX, Zhou AN, Berman BM.

Zhong Xi Yi Jie He Xue Bao. 2010 May;8(5):438-47.

PMID: 20456842 [PubMed – indexed for MEDLINE] Free Article, Related citations

5.Suppression of ongoing experimental arthritis by a chinese herbal formula (huo-luo-xiao-ling dan) involves changes in antigen-induced immunological and biochemical mediators of inflammation.

Yang YH, Rajaiah R, Lee DY, Ma Z, Yu H, Fong HH, Lao L, Berman BM, Moudgil KD.

Evid Based Complement Alternat Med. 2011;2011:642027. Epub 2010 Oct 19.

PMID: 20981317 [PubMed] Free PMC Article, Related citations

6.Modified huo-luo-xiao-ling dan suppresses adjuvant arthritis by inhibiting chemokines and matrix-degrading enzymes.

Nanjundaiah SM, Lee DY, Ma Z, Fong HH, Lao L, Berman BM, Moudgil KD.

Evid Based Complement Alternat Med. 2012;2012:589256. Epub 2012 Mar 7.

PMID: 22474510 [PubMed] Free PMC Article, Related citations

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